abstract：:The arterial to end-tidal PCO2 difference (PaCO2-PE'CO2) was measured in five anaesthetized dogs during controlled ventilation at 0.25 Hz (15 b.p.m.) and during high frequency jet ventilation at 1, 3 and 5 Hz. Because of the slow response of the infra-red carbon dioxide analyser, satisfactory recordings of end-tidal c...

journal_title：British journal of anaesthesia

authors： Mortimer AJ,Cannon DP,Sykes MK

更新日期：1987-02-01 00:00:00

abstract：:Mean venous pressures were measured in 20 patients in whom a catheter, inserted via the external jugular vein, failed to pass centrally. The catheter used had a rounded end and two side holes. Pressures were measured with the patient's head in three different positions. The pressures were compared with the central ven...

journal_title：British journal of anaesthesia

authors： Shah MV,Swai EA,Latto IP

更新日期：1986-12-01 00:00:00

abstract：:The use of atracurium during major abdominal surgery was assessed in 20 infants with hepatic dysfunction caused by biliary atresia. An initial dose of 0.6 mg kg-1 provided excellent intubating conditions in all patients. Subsequent neuromuscular blockade was monitored with a peripheral nerve stimulator and incremental...

journal_title：British journal of anaesthesia

authors： Simpson DA,Green DW

更新日期：1986-11-01 00:00:00

abstract：:The effect of the topical application of a lignocaine-prilocaine cream (EMLA) on the pain of venous cannulation was tested in a double-blind manner. Sixty boys and girls between the ages of 4 and 10 yr who were to undergo surgery participated in the study. No analgesic premedication was given and the venous cannulatio...

journal_title：British journal of anaesthesia

authors： Maunuksela EL,Korpela R

更新日期：1986-11-01 00:00:00

abstract：:The sedation of 50 children aged 6 months to 9 years who had undergone open heart surgery was studied. During artificial ventilation a midazolam infusion was used in conjunction with the administration of morphine (and tubocurarine). Sedation for patients breathing spontaneously with positive airway pressure was conti...

journal_title：British journal of anaesthesia

authors： Booker PD,Beechey A,Lloyd-Thomas AR

更新日期：1986-10-01 00:00:00

abstract：:A mathematical model of a subject breathing from a circle system has been used to follow the course of anaesthetic uptake during the simulated administration of 60% nitrous oxide, 2% halothane and 2% methoxyflurane, under non-rebreathing conditions and with fresh gas flows to the circle system of between 8 and 0.25 li...

journal_title：British journal of anaesthesia

authors： Conway CM

更新日期：1986-10-01 00:00:00

abstract：:The study was performed to determine the ED50 and ED95 of a continuous infusion of the emulsion formulation of propofol during 67% nitrous oxide anaesthesia in 57 patients premedicated with morphine sulphate 0.15 mg kg-1. Anaesthesia was induced with propofol 2 mg kg-1, and maintained before incision with a fixed-rate...

journal_title：British journal of anaesthesia

authors： Spelina KR,Coates DP,Monk CR,Prys-Roberts C,Norley I,Turtle MJ

更新日期：1986-10-01 00:00:00

abstract：:Closed-loop control of neuromuscular blockade, using a semi-continuous infusion of vecuronium, is described. In 28 patients, the average neuromuscular transmission was between 13 and 17% of control. Requirements for vecuronium averaged 1.1 micrograms kg-1 min-1 (0.8-1.5 micrograms kg-1 min-1), being in the same range ...

journal_title：British journal of anaesthesia

authors： de Vries JW,Ros HH,Booij LH

更新日期：1986-10-01 00:00:00

abstract：:This paper describes the use of solenoid valves for the production of binary gas mixtures. The system is controlled by a microprocessor and is capable of delivering accurate flows and concentrations of gases over the ranges commonly used in anaesthesia. Since the flow produced by the valves is pulsatile, a system for ...

journal_title：British journal of anaesthesia

authors： Palayiwa E,Hahn CE,Sugg BR,Lindsay-Scott D,Tyrrell PJ

更新日期：1986-09-01 00:00:00

abstract：:Fentanyl or alfentanil, in doses approximating to those used in clinical practice, was added to the priming fluid of an extracorporeal circuit before the institution of cardiopulmonary bypass (CPB). The concentrations of both drugs in the priming fluid were measured over a 20-min period. The concentration of fentanyl ...

journal_title：British journal of anaesthesia

authors： Skacel M,Knott C,Reynolds F,Aps C

更新日期：1986-09-01 00:00:00

abstract：:"Priming" with alcuronium has been studied in 72 female patients. Blockade of single twitch responses of the adductor pollicis by alcuronium 0.15, 0.2 or 0.3 mg kg-1 could be accelerated by priming with a suitable priming portion of the total dose. Giving alcuronium 0.04 mg kg-1 30 s after the induction of anaesthesia...

journal_title：British journal of anaesthesia

authors： Black AM,Hutton P,el-Hassan KM,Morgan G,Clutton-Brock TH

更新日期：1986-08-01 00:00:00

abstract：:In 40 patients anaesthetized with thiopentone, 66% nitrous oxide and 1% halothane, the effects of a single i.v. dose of nalbuphine 4.5, 8, 15, 25 or 50 mg/70 kg or morphine 3, 5, 10 or 17.5 mg/70 kg on total ventilation and end-tidal carbon dioxide concentration have been measured. Depression of respiration occurred w...

journal_title：British journal of anaesthesia

authors： Klepper ID,Rosen M,Vickers MD,Mapleson WW

更新日期：1986-06-01 00:00:00

abstract：:The insufflation of oxygen at 1 litre kg-1 min-1 via two endobronchial catheters (called continuous flow ventilation (CFV)) maintained a normal PaCO2 and a constant PaO2 in anaesthetized paralysed dogs and in five out of seven cats. In two cats with a high carbon dioxide production, CFV failed to maintain carbon dioxi...

journal_title：British journal of anaesthesia

authors： Perl A,Whitwam JG,Chakrabarti MK,Taylor VM

更新日期：1986-05-01 00:00:00

abstract：:Liver/gas partition coefficients for isoflurane, enflurane, halothane and methoxyflurane increased two-fold in rats killed 16 h after a single injection of 15% ethanol 7 g kg-1. In contrast, blood/gas and brain/gas partition coefficients did not change. Chronic (21 days) ingestion of ethanol increased liver/gas partit...

journal_title：British journal of anaesthesia

authors： Fassoulaki A,Eger EI 2nd

更新日期：1986-05-01 00:00:00

abstract：:Seventy-six Chinese patients aged between 15 and 30 yr, undergoing 3rd molar extraction, were randomly allocated to two groups. One group received halothane and the other isoflurane. The incidence of arrhythmia during surgery under anaesthesia with isoflurane was significantly less than with halothane. Sinus tachycard...

journal_title：British journal of anaesthesia

authors： Rodrigo MR,Moles TM,Lee PK

更新日期：1986-04-01 00:00:00

abstract：:Thirty hypertensive patients scheduled for cholecystectomy or hernia repair under general anaesthesia with thiopentone-fentanyl-nitrous oxide-pancuronium were divided into two groups of 15. One group received metoprolol tablets 200 mg in a slow release form, once daily for at least 2 weeks including the morning of sur...

journal_title：British journal of anaesthesia

authors： Magnusson J,Thulin T,Werner O,Järhult J,Thomson D

更新日期：1986-03-01 00:00:00

abstract：:The efficacy of nitroglycerine, verapamil and nifedipine in controlling post-sternotomy hypertension was compared in four groups of 20 patients anaesthetized with fentanyl 100 micrograms kg-1 undergoing elective coronary artery surgery. Vasodilators were started before surgery and adjusted to maintain systolic arteria...

journal_title：British journal of anaesthesia

authors： van Wezel HB,Bovill JG,Schuller J,Gielen J,Hoeneveld MH

更新日期：1986-03-01 00:00:00

abstract：:Plain bupivacaine 0.5% or 0.75% was injected intrathecally in four groups of 10 patients. Group A received 0.75% bupivacaine 2.7 ml at L3/4, group B 0.5% bupivacaine 4 ml at L3/4, group C 0.75% bupivacaine 2.7 ml at L2/3 and group D 0.75% bupivacaine 2 ml at L3/4. A very wide range of height of block was found in each...

journal_title：British journal of anaesthesia

authors： Logan MR,McClure JH,Wildsmith JA

更新日期：1986-03-01 00:00:00

abstract：:Haemodynamic changes (supraventricular tachycardia, decreases in arterial pressure) were observed during laryngoscopy and intubation of the trachea in a patient receiving nifedipine and verapamil. Before the induced stresses of laryngoscopy and tracheal intubation, these drugs had controlled the patient's arterial pre...

journal_title：British journal of anaesthesia

authors： Gorven AM,Cooper GM,Prys-Roberts C

更新日期：1986-03-01 00:00:00

abstract：:The problems of selection of tracheal tubes, and the need for a rationale, are outlined. Tracheal tubes of 7.5 mm and 8.5 mm i.d. are recommended for female and male patients, respectively. Tracheal size was determined using high pressure-low volume cuffs as measuring devices. The average diameter of the cuff at seal ...

journal_title：British journal of anaesthesia

authors： Chandler M,Crawley BE

更新日期：1986-01-01 00:00:00

abstract：:Maternal and umbilical venous serum naloxone concentrations were measured after the i.v. (30 mothers) or i.m. (seven mothers) injection of naloxone 400 micrograms. Following i.v. naloxone there was rapid transfer to the fetus and therapeutic plasma concentrations could be expected in 1 or 2 min. However, following i.m...

journal_title：British journal of anaesthesia

authors： Hibbard BM,Rosen M,Davies D

更新日期：1986-01-01 00:00:00

abstract：:We studied a cat model simulating laudanosine accumulation in the "anephric" patient. Cardiovascular effects were seen only with the bolus doses of laudanosine 2 mg kg-1, and at plasma laudanosine concentrations unlikely to be achieved clinically. Similarly, EEG and power spectra analysis showed no evidence of epilept...

journal_title：British journal of anaesthesia

authors： Ingram MD,Sclabassi RJ,Cook DR,Stiller RL,Bennett MH

更新日期：1986-01-01 00:00:00

abstract：:The value of the continuous monitoring of end-tidal carbon dioxide concentration as an indicator of the acute intraoperative interruption of pulmonary blood flow, in patients with pre-existing restrictions of pulmonary blood flow undergoing closed heart surgery, is illustrated by two case reports. Decreases in end-tid...

journal_title：British journal of anaesthesia

authors： Schuller JL,Bovill JG,Nijveld A

更新日期：1985-12-01 00:00:00

abstract：:Control measurements of blood flow through and cefoxitin extraction ratios across heart and lungs, liver, kidneys and gut were made under steady-state conditions in awake unrestrained sheep. The studies then were repeated with the same animals anaesthetized with 1.5% halothane or whilst undergoing high thoracic (to ap...

journal_title：British journal of anaesthesia

authors： Runciman WB,Mather LE,Ilsley AH,Carapetis RJ,Upton RN

更新日期：1985-12-01 00:00:00

abstract：:The rate of liquid-phase gastric emptying was determined in seven smokers from the rate of paracetamol absorption after abstaining overnight from cigarettes, and again after smoking two cigarettes within 30 min. There were no significant differences between the maximum paracetamol concentration, the time to reach maxi...

journal_title：British journal of anaesthesia

authors： Petring OU,Adelhøj B,Ibsen M,Brynnum J,Poulsen HE

更新日期：1985-11-01 00:00:00

abstract：:Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system st...

journal_title：British journal of anaesthesia

authors： Fahey MR,Rupp SM,Canfell C,Fisher DM,Miller RD,Sharma M,Castagnoli K,Hennis PJ

更新日期：1985-11-01 00:00:00

abstract：:The electroencephalogram (EEG) was monitored through all phases of enflurane anaesthesia in dental outpatients with a history of cerebral convulsions which had been well controlled with anticonvulsant drugs. Abnormal EEG activity which differed from the background activity was observed in three patients. Their case re...

journal_title：British journal of anaesthesia

authors： Yamashiro M,Sumitomo M,Furuya H

更新日期：1985-10-01 00:00:00

abstract：:The analgesic effects and bioavailability of a slow-release preparation of morphine (Duromorph) were studied in 12 patients with acute postoperative pain. Duromorph produced significant analgesia within 1-2 h of administration i.m., and there was a progressive decrease in the mean pain score for at least 8 h. None of ...

journal_title：British journal of anaesthesia

authors： Charway CL,Calvey TN,Williams NE,Murray GR

更新日期：1985-10-01 00:00:00

abstract：:The effects of the inhalation of 50% nitrous oxide on somatosensory evoked potentials during a fentanyl-oxygen anaesthetic technique for central nervous system surgery were evaluated. The latency and amplitude of the first cortical wave were obtained using conventional somatosensory techniques with median or posterior...

journal_title：British journal of anaesthesia

authors： Sloan TB,Koht A

更新日期：1985-09-01 00:00:00

abstract：:The new emulsion formulation of di-isopropyl phenol (propofol) was compared with methohexitone and thiopentone for induction of anaesthesia in day cases. Propofol produced significantly smoother induction of anaesthesia, but caused more cardiovascular and respiratory depression. Pain on injection was significantly les...

journal_title：British journal of anaesthesia

authors： Mackenzie N,Grant IS

更新日期：1985-08-01 00:00:00

abstract：:The fresh gas flow rate necessary to prevent rebreathing in T-piece anaesthesia is well established at twice total ventilation. The minimum reservoir volume to avoid air dilution of anaesthetic gases in the alveolus at this flow rate is, however, undecided. A lung model was constructed to represent spontaneous respira...

journal_title：British journal of anaesthesia

authors： Naunton A

更新日期：1985-08-01 00:00:00

abstract：:The neuromuscular blocking effects of equipotent doses of the three putative metabolites of vecuronium (3-hydroxy vecuronium, 17-hydroxy vecuronium and 3,17-dihydroxy vecuronium) were compared with those of an equipotent dose of vecuronium. Results obtained with the liver excluded from the circulation and after intrap...

journal_title：British journal of anaesthesia

authors： Bencini AF,Houwertjes MC,Agoston S

更新日期：1985-08-01 00:00:00

abstract：:An histaminoid reaction after the administration of thiopentone and atracurium is described. Serial blood sampling showed no evidence of complement activation. Intradermal testing 6 weeks later yielded a positive result with atracurium (1 in 1000), but not with thiopentone. The clinical course of the reaction and the ...

journal_title：British journal of anaesthesia

authors： Lavery GG,Boyle MM,Mirakhur RK

更新日期：1985-08-01 00:00:00

abstract：:Following a paravertebral surgical incision, mature, female rats under ether anaesthesia were exposed to either 3% nitrous oxide, continuously for 48 h, or 50% nitrous oxide, 4 h each day for 7 days. For each exposure group, a similar number of rats was exposed to atmospheres containing no nitrous oxide. Wound healing...

journal_title：British journal of anaesthesia

authors： Algie TA,Seth A,Barbenel JC,Galloway DJ,Gray WM,Spence AA

更新日期：1985-06-01 00:00:00

abstract：:Five-year survival following cardiac transplantation approaches 50% and such patients occasionally present for non-cardiac surgery. The application of a simple general anaesthetic technique is described in a patient undergoing minor surgery, and the problems involved in managing heart transplant recipients are discuss...

journal_title：British journal of anaesthesia

authors： Bricker SR,Sugden JC

更新日期：1985-06-01 00:00:00

abstract：:Cardiac rate and rhythm were compared in 60 patients having dental extractions under conventional general anaesthesia using halothane, enflurane or isoflurane to supplement nitrous oxide in oxygen. The incidence of arrhythmia was higher in the halothane group when compared with both the enflurane (P less than 0.05) an...

journal_title：British journal of anaesthesia

authors： Casson WR,Jones RM

更新日期：1985-05-01 00:00:00

abstract：:Seven patients are described in whom a prophylactic blood patch was instituted within 15 min of accidental dural puncture. Five of the patients received extradural anaesthesia before the blood patch, and one after the blood patch had been performed. In three of these patients further "top-up" doses of local anaestheti...

journal_title：British journal of anaesthesia

authors： Quaynor H,Corbey M

更新日期：1985-05-01 00:00:00

abstract：:The effect of the intrathecal administration of diamorphine on the hyperglycaemic, adrenocortical and cardiovascular responses to major colonic surgery were investigated, and the results compared with those obtained in a similar group of patients receiving low doses of fentanyl. In the group receiving intrathecal diam...

journal_title：British journal of anaesthesia

authors： Child CS,Kaufman L

更新日期：1985-04-01 00:00:00

abstract：:Zomepirac 100 mg and dihydrocodeine 30 mg were compared with placebo in a controlled randomized, double-blind, single-dose postoperative study. Patients continued to receive either zomepirac or dihydrocodeine for pain relief for 5 days at home in a double-blind study, being allowed to titrate the consumption of tablet...

journal_title：British journal of anaesthesia

authors： McQuay HJ,Bullingham RE,Moore RA,Carroll D,Evans PJ,O'Sullivan G,Collin J,Lloyd JW

更新日期：1985-04-01 00:00:00

abstract：:In a prospective double-blind study, single dose lumbar extradural blockade was instituted in 80 healthy male patients undergoing lower abdominal surgery. Patients were assigned randomly to one of four groups. Each group received treatment with 0.5% bupivacaine 20 ml containing adrenaline 1:200 000. To this solution w...

journal_title：British journal of anaesthesia

authors： Rucci FS,Cardamone M,Migliori P

更新日期：1985-03-01 00:00:00